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Record - 1 of 13   [TOP]
Compound IDNVIC0017
Compound Structure
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InhibitorPyrazofurin
SMILESC(C1C(C(C(O1)C2=NNC(=C2O)C(=O)N)O)O)O
PubChem ID 135413551
Drug Bank ID\N
ChemSpider ID10570780
TargetReplication
Assay TypeCPE visual
Assay Description\N
Assay Source\N
Cell TypeVero E6 cells
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)259.22
H-bond Acceptor8
H-bond Donor6
No. of Rotatable Bonds3
LogP-1.60
Topological Polar Surface Area (Å)161.92
PUBMED ID16641448
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 2 of 13   [TOP]
Compound IDNVIC0034
Compound Structure
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InhibitorAB00991123
SMILESC1CC(=CC2=CC=CC=C21)S(=O)(=O)NC3=CC=C(C=C3)N4C=NN=N4
PubChem ID 17483530
Drug Bank ID\N
ChemSpider ID17026724
TargetReplication
Assay TypeCytotoxicity kit
Assay Description10-point concentration response assay
Assay SourceEnamine Ltd. (Kiev, Ukraine)
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)3900.0
OutcomeInhibition of virus-induced cytopathic effect
Molecular Weight (in g/mol)353.40
H-bond Acceptor4
H-bond Donor1
No. of Rotatable Bonds4
LogP4.37
Topological Polar Surface Area (Å)97.63
PUBMED ID24735442
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994909/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 3 of 13   [TOP]
Compound IDNVIC0053
Compound Structure
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InhibitorAB00993210
SMILESCN(C)S(=O)(=O)C1=CC2=C(C=C1)N(CC2)S(=O)(=O)C3=CC=CS3
PubChem ID 25672978
Drug Bank ID\N
ChemSpider ID22443136
TargetReplication
Assay TypeCytotoxicity kit
Assay Description10-point concentration response assay
Assay SourceEnamine Ltd. (Kiev, Ukraine)
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)7800.0
OutcomeInhibition of virus-induced cytopathic effect
Molecular Weight (in g/mol)372.48
H-bond Acceptor7
H-bond Donor0
No. of Rotatable Bonds4
LogP1.71
Topological Polar Surface Area (Å)119.76
PUBMED ID24735442
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994909/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 4 of 13   [TOP]
Compound IDNVIC0065
Compound Structure
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InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetReplication
Assay TypeHTS immunolabeling assay
Assay DescriptionHRP-chemiluminescent
Assay Source\N
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)3356.0
OutcomeVirus inhibition
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID18313148
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 5 of 13   [TOP]
Compound IDNVIC0065
Compound Structure
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InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetReplication
Assay TypeHTS immunolabeling assay
Assay DescriptionFluorescent immunodetection
Assay Source\N
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)6041.0
OutcomeVirus inhibition
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID18313148
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
Curator Email IDpriyankapaul008@gmail.com

                  
Record - 6 of 13   [TOP]
Compound IDNVIC0065
Compound Structure
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InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetReplication
Assay TypeCPE visual
Assay Description\N
Assay Source\N
Cell TypeVero E6 cells
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID16641448
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 7 of 13   [TOP]
Compound IDNVIC0067
Compound Structure
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Inhibitor09167(2,2,2-trifluoro-N-[3-(N-naphthylcarbamoyl)(4,5,6,7-tetrahydrobenzo [beta]thiophen-2-yl)]acetamide)
SMILESC1CCC2=C(C1)C(=C(S2)NC(=O)C(F)(F)F)C(=O)NC3=CC=CC4=CC=CC=C43
PubChem ID 4293368
Drug Bank ID\N
ChemSpider ID3499535
TargetReplication
Assay TypeReporter assay
Assay Description\N
Assay SourceVitas-M Laboratory
Cell TypeHEK 293T cells
IC50 (nM)0.0
EC50 (in nM)72.3
OutcomeAblated NiV-LUC2AM activity
Molecular Weight (in g/mol)418.43
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bonds6
LogP6.53
Topological Polar Surface Area (Å)86.44
PUBMED ID24680955
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 8 of 13   [TOP]
Compound IDNVIC0067
Compound Structure
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Inhibitor09167(2,2,2-trifluoro-N-[3-(N-naphthylcarbamoyl)(4,5,6,7-tetrahydrobenzo [beta]thiophen-2-yl)]acetamide)
SMILESC1CCC2=C(C1)C(=C(S2)NC(=O)C(F)(F)F)C(=O)NC3=CC=CC4=CC=CC=C43
PubChem ID 4293368
Drug Bank ID\N
ChemSpider ID3499535
TargetReplication
Assay TypeReporter assay
Assay Description\N
Assay SourceVitas-M Laboratory
Cell TypeHEK 293T cells
IC50 (nM)0.0
EC50 (in nM)254.0
OutcomeAblated NiV-GFP2AM avtivity
Molecular Weight (in g/mol)418.43
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bonds6
LogP6.53
Topological Polar Surface Area (Å)86.44
PUBMED ID24680955
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 9 of 13   [TOP]
Compound IDNVIC0067
Compound Structure
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Inhibitor09167(2,2,2-trifluoro-N-[3-(N-naphthylcarbamoyl)(4,5,6,7-tetrahydrobenzo [beta]thiophen-2-yl)]acetamide)
SMILESC1CCC2=C(C1)C(=C(S2)NC(=O)C(F)(F)F)C(=O)NC3=CC=CC4=CC=CC=C43
PubChem ID 4293368
Drug Bank ID\N
ChemSpider ID3499535
TargetReplication
Assay TypeReporter assay
Assay Description\N
Assay SourceVitas-M Laboratory
Cell TypeHEK 293T cells
IC50 (nM)0.0
EC50 (in nM)28.9
OutcomeAblated NiV-MY-99 activity
Molecular Weight (in g/mol)418.43
H-bond Acceptor8
H-bond Donor2
No. of Rotatable Bonds6
LogP6.53
Topological Polar Surface Area (Å)86.44
PUBMED ID24680955
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 10 of 13   [TOP]
Compound IDNVIC0085
Compound Structure
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InhibitorEICAR
SMILESC#CC1=C(N=CN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 453180
Drug Bank ID\N
ChemSpider ID399153
TargetReplication
Assay TypeCPE visual
Assay Description\N
Assay Source\N
Cell TypeVero E6 cells
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)267.24
H-bond Acceptor7
H-bond Donor5
No. of Rotatable Bonds3
LogP-1.80
Topological Polar Surface Area (Å)130.83
PUBMED ID16641448
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 11 of 13   [TOP]
Compound IDNVIC0110
Compound Structure
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Inhibitor6-Azauridine
SMILESC1=NN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
PubChem ID 5901
Drug Bank ID\N
ChemSpider ID203593
TargetReplication
Assay TypeCPE visual
Assay Description\N
Assay Source\N
Cell TypeVero E6 cells
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)245.19
H-bond Acceptor8
H-bond Donor4
No. of Rotatable Bonds2
LogP-1.90
Topological Polar Surface Area (Å)131.69
PUBMED ID16641448
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 12 of 13   [TOP]
Compound IDNVIC0118
Compound Structure
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Inhibitor25-hydroxycholesterol
SMILESCC(CCCC(C)(C)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
PubChem ID 65094
Drug Bank IDDB04705
ChemSpider ID58604
TargetReplication
Assay TypePlaque assay
Assay DescriptionVirus Titre Reduction assay
Assay SourceProduced within mammalian species
Cell TypeHeLa cells
IC50 (nM)1000.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)402.66
H-bond Acceptor2
H-bond Donor2
No. of Rotatable Bonds5
LogP8.55
Topological Polar Surface Area (Å)40.46
PUBMED ID23273844
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698975/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 13 of 13   [TOP]
Compound IDNVIC0128
Compound Structure
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InhibitorAB00992391
SMILESC1=CC(=CC=C1NS(=O)(=O)C2=CC(=C(C=C2)F)F)N3C=NN=N3
PubChem ID 8189728
Drug Bank ID\N
ChemSpider ID6491411
TargetReplication
Assay TypeCytotoxicity kit
Assay Description10-point concentration response assay
Assay SourceEnamine Ltd. (Kiev, Ukraine)
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)11700.0
OutcomeInhibition of virus-induced cytopathic effect
Molecular Weight (in g/mol)337.31
H-bond Acceptor6
H-bond Donor1
No. of Rotatable Bonds4
LogP2.78
Topological Polar Surface Area (Å)97.63
PUBMED ID24735442
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994909/
Curator Email IDkanikatuteja@gmail.com