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Compound IDNVIC0089
Compound Structure
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InhibitorGYY4137[morpholin-4-ium-4-methoxyphenyl(morpholino)phosphinodithioate]
SMILESCOC1=CC=C(C=C1)P(=S)(N2CCOCC2)S
PubChem ID 46937262
Drug Bank ID\N
ChemSpider ID26232138
TargetViral replication and proinflammatory gene expression.
Assay TypeCPE visual
Assay DescriptionPlaque assay
Assay SourceSigma-Aldrich (St. Louis, MO, USA)
Cell TypeSAE cells
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeReplication and inflammatory chemokine production induced by Nipah virus (NiV-B) was inhibited
Molecular Weight (in g/mol)289.35
H-bond Acceptor3
H-bond Donor0
No. of Rotatable Bonds3
LogP2.58
Topological Polar Surface Area (Å)63.60
PUBMED ID25740991
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442521/
Curator Email IDnishisharmacool14@gmail.com