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Compound IDNVIC0086
Compound Structure
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InhibitorR1479
SMILESC1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
PubChem ID 457388
Drug Bank ID\N
ChemSpider ID402579
TargetRNA-dependent RNA polymerase (RdRp)
Assay TypeCPE visual
Assay DescriptionNon-linear regression analysis
Assay SourceCarbosynth US LLC, San Diego, CA, USA
Cell TypeHeLa cells
IC50 (nM)0.0
EC50 (in nM)13550.0
OutcomeReduction in cell viability
Molecular Weight (in g/mol)284.23
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-2.10
Topological Polar Surface Area (Å)140.97
PUBMED ID28629988
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648002/
Curator Email IDkanikatuteja@gmail.com