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Compound IDNVIC0092
Compound Structure
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InhibitorFavipiravir
SMILESC1=C(N=C(C(=O)N1)C(=O)N)F
PubChem ID 492405
Drug Bank IDDB12466
ChemSpider ID431002
TargetRNA-dependent RNA polymerase (RdRp)
Assay TypeCytotoxicity kit
Assay DescriptionPlaque assay
Assay SourceToyama Chemical Company, Ltd. (Toyama, Japan)
Cell TypeVero CCL81 cells
IC50 (nM)0.0
EC50 (in nM)14570.0
OutcomeReduction of viral titres in a dose-dependent manner for recombinant NiV expressing Gaussia luciferase and eGFP (rNiV-Gluc-eGFP)
Molecular Weight (in g/mol)157.10
H-bond Acceptor4
H-bond Donor2
No. of Rotatable Bonds1
LogP-0.30
Topological Polar Surface Area (Å)89.10
PUBMED ID29765101
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954062/
Curator Email IDanshu@imtech.res.in