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Compound IDNVIC0017
Compound Structure
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InhibitorPyrazofurin
SMILESC(C1C(C(C(O1)C2=NNC(=C2O)C(=O)N)O)O)O
PubChem ID 135413551
Drug Bank ID\N
ChemSpider ID10570780
TargetOrotidine 5?-monophosphate decarboxylase
Assay TypeReporter assay
Assay Description\N
Assay SourceToronto Research Chemicals
Cell TypeHEK 293T cells
IC50 (nM)0.0
EC50 (in nM)281.0
OutcomeInhibition cellular of Pyrimidine biosynthesis
Molecular Weight (in g/mol)259.22
H-bond Acceptor8
H-bond Donor6
No. of Rotatable Bonds3
LogP-1.60
Topological Polar Surface Area (Å)161.92
PUBMED ID24680955
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100748/
Curator Email IDkanikatuteja@gmail.com