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Compound IDNVIC0118
Compound Structure
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Inhibitor25-hydroxycholesterol
SMILESCC(CCCC(C)(C)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
PubChem ID 65094
Drug Bank IDDB04705
ChemSpider ID58604
TargetReplication
Assay TypePlaque assay
Assay DescriptionVirus Titre Reduction assay
Assay SourceProduced within mammalian species
Cell TypeHeLa cells
IC50 (nM)1000.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)402.66
H-bond Acceptor2
H-bond Donor2
No. of Rotatable Bonds5
LogP8.55
Topological Polar Surface Area (Å)40.46
PUBMED ID23273844
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698975/
Curator Email IDkanikatuteja@gmail.com