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Compound IDNVIC0112
Compound Structure
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InhibitorMibefradil
SMILESCC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)COC)C=C(C=C2)F
PubChem ID 60663
Drug Bank ID\N
ChemSpider ID54673
TargetT-type calcium channels antagonist
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source\N
Cell TypeVero cells
IC50 (nM)6110.0
EC50 (in nM)0.0
OutcomeCalcium channel blockage
Molecular Weight (in g/mol)495.64
H-bond Acceptor6
H-bond Donor1
No. of Rotatable Bonds12
LogP6.43
Topological Polar Surface Area (Å)67.45
PUBMED ID20668647
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
Curator Email IDkanikatuteja@gmail.com