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Compound IDNVIC0123
Compound Structure
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InhibitorTetrandine
SMILESCN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
PubChem ID 73078
Drug Bank ID\N
ChemSpider ID65868
TargetL/T-type Calcium channel antagonist
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source\N
Cell TypeVero cells
IC50 (nM)654800.0
EC50 (in nM)0.0
OutcomeCalcium channel blockage
Molecular Weight (in g/mol)622.76
H-bond Acceptor8
H-bond Donor0
No. of Rotatable Bonds4
LogP6.09
Topological Polar Surface Area (Å)61.86
PUBMED ID20668647
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
Curator Email IDkanikatuteja@gmail.com