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Compound IDNVIC0031
Compound Structure
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InhibitorAmiloride
SMILESC1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N
PubChem ID 16231
Drug Bank ID\N
ChemSpider ID15403
TargetInhibitor of sodium channels
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source\N
Cell TypeVero cells
IC50 (nM)656470.0
EC50 (in nM)0.0
OutcomeSodium channel blockage
Molecular Weight (in g/mol)229.63
H-bond Acceptor6
H-bond Donor4
No. of Rotatable Bonds2
LogP-1.10
Topological Polar Surface Area (Å)159.29
PUBMED ID20668647
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
Curator Email IDkanikatuteja@gmail.com