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Record - 1 of 5   [TOP]
Compound IDNVIC0065
Compound Structure
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InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetCrossing of the blood-brain barrier
Assay TypeClinical trial, non randomized
Assay DescriptionFollow-up of pateints
Assay Source\N
Cell Type\N
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeReduction in mortality
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID11409437
Referencehttps://www.ncbi.nlm.nih.gov/pubmed/11409437
Curator Email IDkanikatuteja@gmail.com

                  
Record - 2 of 5   [TOP]
Compound IDNVIC0065
Compound Structure
DOWNLOAD:
InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetReplication
Assay TypeHTS immunolabeling assay
Assay DescriptionHRP-chemiluminescent
Assay Source\N
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)3356.0
OutcomeVirus inhibition
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID18313148
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 3 of 5   [TOP]
Compound IDNVIC0065
Compound Structure
DOWNLOAD:
InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetReplication
Assay TypeHTS immunolabeling assay
Assay DescriptionFluorescent immunodetection
Assay Source\N
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)6041.0
OutcomeVirus inhibition
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID18313148
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
Curator Email IDpriyankapaul008@gmail.com

                  
Record - 4 of 5   [TOP]
Compound IDNVIC0065
Compound Structure
DOWNLOAD:
InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetReplication
Assay TypeCPE visual
Assay Description\N
Assay Source\N
Cell TypeVero E6 cells
IC50 (nM)0.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID16641448
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
Curator Email IDkanikatuteja@gmail.com

                  
Record - 5 of 5   [TOP]
Compound IDNVIC0065
Compound Structure
DOWNLOAD:
InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetRNA replication
Assay TypeCPE visual
Assay DescriptionNon-linear regression analysis
Assay SourceValeant
Cell TypeHeLa cells
IC50 (nM)4180.0
EC50 (in nM)0.0
OutcomeReduce the spread and infection of NiV
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID19889926
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888097/
Curator Email IDnishisharmacool14@gmail.com