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Compound IDNVIC0025
Compound Structure
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InhibitorZHAWOC21026
SMILESCN(C(=O)COC1=CC=CC2=C1OC(C)(C)C2)C1=NC2=C(CCCC2)S1
PubChem ID 152138821
Drug Bank ID\N
ChemSpider ID\N
TargetRNA-dependent RNA polymerase (RdRp)
Assay TypeRealTime-Glo MT cell viability assay
Assay Descriptionvirus inhibition assay
Assay Source\N
Cell TyperNiV-EGFP, PGSA745-EFNB2
IC50 (nM)80.0
EC50 (in nM)0.0
Outcomeinhibition of RNA-dependent RNA polymerase (RdRp)
Molecular Weight (in g/mol)372.48
H-bond Acceptor5
H-bond Donor0
No. of Rotatable Bonds5
LogP3.78
Topological Polar Surface Area (Å)79.90
PUBMED ID34724816
Referencehttps://pubmed.ncbi.nlm.nih.gov/34724816/
Curator Email IDbhupender.thakur855@gmail.com