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Compound IDNVIC0084
Compound Structure
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Inhibitor4-OH-tamoxifen
SMILESCCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
PubChem ID 449459
Drug Bank ID\N
ChemSpider ID4447687
TargetRelease ER calcium stores
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source\N
Cell TypeVero cells
IC50 (nM)7510.0
EC50 (in nM)0.0
OutcomeInhibition of henipavirus replication
Molecular Weight (in g/mol)387.52
H-bond Acceptor3
H-bond Donor1
No. of Rotatable Bonds8
LogP8.73
Topological Polar Surface Area (Å)32.70
PUBMED ID20668647
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
Curator Email IDkanikatuteja@gmail.com