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Compound IDNVIC0099
Compound Structure
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InhibitorRottlerin
SMILESCC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C3=C(C(=C2O)C(=O)C=CC4=CC=CC=C4)OC(C=C3)(C)C)O)O
PubChem ID 5281847
Drug Bank ID\N
ChemSpider ID4445144
TargetInhibits PKC mediated pathways
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source\N
Cell TypeVero cells
IC50 (nM)19820.0
EC50 (in nM)0.0
OutcomeInhibition of viral replication
Molecular Weight (in g/mol)516.55
H-bond Acceptor8
H-bond Donor5
No. of Rotatable Bonds6
LogP5.12
Topological Polar Surface Area (Å)144.52
PUBMED ID20668647
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
Curator Email IDkanikatuteja@gmail.com