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Compound IDNVIC0122
Compound Structure
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InhibitorDantrolene
SMILESC1C(=O)NC(=O)N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]
PubChem ID 6914273
Drug Bank ID\N
ChemSpider ID5036403
TargetInhibitor of ryanodine receptor mediated calcium release from the ER
Assay TypeHTS immunolabeling assay
Assay DescriptionNon-linear regression analysis
Assay Source\N
Cell TypeVero cells
IC50 (nM)12410.0
EC50 (in nM)0.0
OutcomeInhibition of henipavirus replication
Molecular Weight (in g/mol)314.26
H-bond Acceptor5
H-bond Donor0
No. of Rotatable Bonds4
LogP2.89
Topological Polar Surface Area (Å)106.02
PUBMED ID20668647
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910441/
Curator Email IDkanikatuteja@gmail.com