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Compound IDNVIC0131
Compound Structure
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Inhibitor4-oxo-1,4-Dihydroquinoline-3,5-dicarboxylic Acid
SMILESC1=CC(=C2C(=C1)NC=C(C2=O)C(=O)O)C(=O)O
PubChem ID 91619677
Drug Bank ID\N
ChemSpider ID62941102
Targetfusion glycoprotein (NiV-F)
Assay TypeCell-cell fusion assay
Assay DescriptionSize of the syncytia
Assay Source\N
Cell TypeVero cells
IC50 (nM)0.0
EC50 (in nM)8000.0
OutcomeInhibit NiV-induced virus-cell and cell-cell fusion
Molecular Weight (in g/mol)233.18
H-bond Acceptor6
H-bond Donor3
No. of Rotatable Bonds2
LogP1.46
Topological Polar Surface Area (Å)103.70
PUBMED ID19499921
Referencehttps://pubs.acs.org/doi/full/10.1021/jm900411s
Curator Email IDkanikatuteja@gmail.com