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Record - 1 of 2   [TOP]
Compound IDNVIC0054
Compound Structure
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InhibitorChloroquine
SMILESCCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
PubChem ID 2719
Drug Bank IDDB00608
ChemSpider ID2618
TargetRNA replication
Assay TypeCPE visual
Assay DescriptionNon-linear regression analysis
Assay SourceSigma
Cell TypeHeLa cells
IC50 (nM)620.0
EC50 (in nM)0.0
OutcomeReduce the spread and infection of NiV
Molecular Weight (in g/mol)319.88
H-bond Acceptor3
H-bond Donor1
No. of Rotatable Bonds8
LogP4.14
Topological Polar Surface Area (Å)28.16
PUBMED ID19889926
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888097/
Curator Email IDnishisharmacool14@gmail.com

                  
Record - 2 of 2   [TOP]
Compound IDNVIC0065
Compound Structure
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InhibitorRibavirin
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
PubChem ID 37542
Drug Bank IDDB00811
ChemSpider ID34439
TargetRNA replication
Assay TypeCPE visual
Assay DescriptionNon-linear regression analysis
Assay SourceValeant
Cell TypeHeLa cells
IC50 (nM)4180.0
EC50 (in nM)0.0
OutcomeReduce the spread and infection of NiV
Molecular Weight (in g/mol)244.21
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bonds3
LogP-3.00
Topological Polar Surface Area (Å)143.72
PUBMED ID19889926
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888097/
Curator Email IDnishisharmacool14@gmail.com