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Antimicrobial Resistance Knowledgebase
Transcriptomics Antibiotics Exposure

Transcriptomics Antibiotics Exposure

S.no. Organism Project Title Project Database Project Accession Antibiotic Name Release Date Samples
1 Acinetobacter baumannii The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model GEO PRJNA265162 Doripenem Nov-30-2014 22
2 Acinetobacter baumannii Transcriptional response to carbapenem treatment in Acinetobacter baumannii GEO PRJNA787205 Meropenem May-20-2022 18
3 Escherichia coli Prediction of antibiotic resistance by large-scale phenotypic and genotypic data GEO PRJNA255254 Cefoperazone, Cefixime Jul-14-2014 42
4 Escherichia coli Global gene expression profiling and antibiotic susceptibility after repeated exposure to the carbon monoxide-releasing molecule-2 (CORM-2) in multidrug-resistant ESBL-producing uropathogenic Escherichia coli GEO PRJNA345430 Cefotaxime Oct-05-2016 16
5 Escherichia coli Tellurite-mediated cefotaxime (CTX) potentiation GEO PRJNA171495 Cefotaxime Jul-27-2012 9
6 Escherichia coli Expression of Escherichia coli treated with cefsulodin and mecillinam GEO PRJNA108353 Cefsulodin Jul-15-2008 61
7 Escherichia coli Expression of Escherichia coli treated with cefsulodin and mecillinam, alone at the minimum inhibitory concentration GEO PRJNA109011 Cefsulodin Jul-15-2008 18
8 Escherichia coli Expression of Escherichia coli treated with cefsulodin and mecillinam, alone and in combination GEO PRJNA109009 Cefsulodin Jul-15-2008 43
9 Escherichia coli Comparative transcriptomic response analysis of Escherichia coli K-12 MG1655 to nine antibiotics GEO PRJNA910221 Ceftazidime, Imipenem Dec-08-2022 33
10 Escherichia coli Transcriptional alterations of virulence-associated genes in extended spectrum beta-lactamase (ESBL)-producing uropathogenic Escherichia coli during morphologic transitions induced by ineffective antibiotics GEO PRJNA389257 Ceftibuten Jun-05-2017 16
11 Escherichia coli Transcriptional profiling of extraintestinal Escherichia coli exposed to cranberry pomace extracts alone or in combination with ceftriaxone GEO PRJNA844238 Ceftriaxone Jun-01-2022 12
12 Escherichia coli Expression profiling of E. coli in three media treated with antibiotics GEO PRJNA669053 Ceftriaxone, Meropenem Oct-13-2020 30
13 Escherichia coli Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 E. coli to Carbapenem Exposure GEO PRJNA1141951 Ertapenem Jul-30-2024 11
14 Klebsiella pneumoniae Inappropriate use of antibiotics exacerbates inflammation through OMVs-induced pyroptosis in multidrug-resistant Klebsiella pneumoniae infection GEO PRJNA757732 Imipenem Aug-28-2021 6
15 Klebsiella pneumoniae Klebsiella pneumoniae strain:BAMC 07-18 GEO PRJNA262671 Imipenem, Meropenem, Doripenem Jan-01-2015 6
16 Klebsiella pneumoniae Network integrative genomic and transcriptomic analysis of carbapenem-resistant Klebsiella pneumoniae strains identifies genes for resistance and virulence GEO PRJNA475291 Meropenem Jun-10-2018 4
17 Klebsiella pneumoniae Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states GEO PRJNA747165 Meropenem Jan-27-2023 35
18 Neisseria gonorrhoeae External stresses affect gonococcal type 4 pilus dynamics GEO PRJNA800749 Ceftriaxone Feb-02-2022 18
19 Pseudomonas aeruginosa Effect of long-term exposure of platinum nanopariticles on gene expression of Pseudomonas aeruginosa PAO1 GEO PRJNA903796 Imipenem Dec-01-2023 9
20 Pseudomonas aeruginosa Targeted transposon screening in bacteria by CRISPR/Cas12k-guided transposase GEO PRJNA691969 Imipenem Aug-10-2021 10
21 Pseudomonas aeruginosa Phage-phage competition and biofilms affect interactions between two virulent bacteriophages and Pseudomonas aeruginosa GEO PRJNA1132182 Meropenem Jul-17-2024 12
22 Pseudomonas aeruginosa Transcriptional changes between mono- and dual-species biofilms of Pseudomonas aeruginosa and Candida albicans, ± meropenem treatment. (Mono- and dual-species biofilms of C. albicans and P. aeruginosa were grown in vitro, with or without meropenem treatment. Four biological replicates were included, with six samples per replicate. ) GEO PRJNA703054 Meropenem Nov-11-2022 24
23 Pseudomonas aeruginosa Pseudomonas aeruginosa Ceftolozane-Tazobactam Resistance Development Requires Multiple Mutations Leading to Overexpression and Structural Modification of AmpC. GEO PRJNA252560 Meropenem, Imipenem Jun-12-2014 16
24 Pseudomonas aeruginosa Perturbation-Specific Transcriptional Mapping for unbiased target elucidation of antibiotics GEO PRJNA1055047 Meropenem, Imipenem Oct-11-2024 1059
25 Salmonella enterica Evolutionary barriers to horizontal gene transfer in macrophage associated Salmonella GEO PRJNA927019 Ciprofloxacin Jan-27-2023 18
26 Salmonella enterica High-throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella During Stress and Infection- Barseq3 (LB, ceftriaxone, ciprofloxacin, azithromycin) GEO PRJNA1088554 Ciprofloxacin Apr-12-2024 40
27 Salmonella enterica Salmonella enteritidis ciprofloxacin resistance effect on transcription in LB GEO PRJNA114743 Ciprofloxacin Mar-06-2009 12
28 Staphylococcus aureus Comparative virulence studies and transcriptome analysis of Staphylococcus aureus strains isolated from animals GEO PRJNA313454 Methicillin Mar-02-2016 4
29 Staphylococcus aureus The Staphylococcus aureus α-Acetolactate Synthase ALS Confers Resistance to Nitrosative Stress GEO PRJNA388956 Methicillin, Oxacillin Jun-02-2017 4
30 Streptococcus pneumoniae Inducible expression of macrolide efflux in Streptococcus pneumoniae is controlled by transcriptional attenuation of the mef(E)/mel operon GEO PRJNA235338 Erythromycin, Spiromycin Feb-01-2014 46
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