| Gene name | Strain | Protein ID | Product | Drug class | Antibiotic name | Broad MOR | MOR | Enzyme class | Similar mechanisms in other species | IS elements | Chromosome vs plasmid mediated | Pathway | Pan genome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dfrA10 | Acinetobacter_baumannii__str._AYE | CAM88389.1 | "Dihydrofolate reductase type A10 (Dihydrofolate reductase type X) (DHFRX)" | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Klebsiella pneumoniae; Salmonella enterica | Not found | Chromosome mediated | K19643 | Not mapped |
| dfrA1 | Acinetobacter_baumannii_Aci20 | WP_071846293.1 | trimethoprim-resistant dihydrofolate reductase DfrA1 | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Enterobacter aerogenes; Enterobacter cloacae; Klebsiella pneumoniae; PseudomoNot founds aeruginosa; Salmonella enterica; Shigella dysenteriae; Shigella flexneri; Shigella sonnei | Not found | Chromosome mediated | K18589 | ACCESSORY |
| dfrA7 | Acinetobacter_baumannii_strain_BM4674 | ACS44716.1 | dihydrofolate reductase type A7 | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Enterobacter cloacae; Klebsiella pneumoniae; Salmonella enterica | mobile_element_type=integron:class I | Chromosome mediated | K18589 | ACCESSORY |
| dhfrI | Acinetobacter_baumannii_AYE | WP_000777554.1 | Dihydrofolate reductase (EC 1.5.1.3) | NA | Trimethoprim | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | K18589 | ACCESSORY |
| dfrA12 | Acinetobacter_baumannii_strain_SMSZ2 | ANQ47254.1 | dihydrofolate reductase | diaminopyrimidine antibiotic | trimethoprim | target modification | antibiotic target replacement | trimethoprim resistant dihydrofolate reductase dfr | Enterobacter aerogenes; Enterobacter cloacae; Enterococcus faecium; Klebsiella pneumoniae; Salmonella enterica;Shigella sonnei | Not found | Chromosome mediated | K18590 | Not mapped |
A comprehensive repository of Acinetobacter baumannii to understand the molecular landscape of antimicrobial resistance
