| Gene name |
Strain |
Protein ID |
Product |
Drug class |
Antibiotic name |
Broad MOR |
MOR |
Enzyme class |
Similar mechanisms in other species |
IS elements |
Chromosome vs plasmid mediated |
Pathway |
Pan genome |
| armA | Acinetobacter_baumannii_SMC_Paed_Ab_BL01 | WP_000359986.1 | ArmA family 16S rRNA | aminoglycoside antibiotic | dibekacin; amikacin;gentamicin C; Sisomicin; Netilmicin; KaNot mappedmycin A; Tobramycin; Isepamicin; G418; Arbekacin | target modification | antibiotic target alteration | NA | Enterobacter cloacae; Klebsiella pneumoniae; PseudomoNot founds aeruginosa; Salmonella enterica | Not found | Chromosome mediated | K18845 | ACCESSORY
|
| dfrA10 | Acinetobacter_baumannii__str._AYE | CAM88389.1 | "Dihydrofolate reductase type A10 (Dihydrofolate
reductase type X) (DHFRX)" | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Klebsiella pneumoniae; Salmonella enterica | Not found | Chromosome mediated | K19643 | Not mapped
|
| dfrA1 | Acinetobacter_baumannii_Aci20 | WP_071846293.1 | trimethoprim-resistant dihydrofolate reductase DfrA1 | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Enterobacter aerogenes; Enterobacter cloacae; Klebsiella pneumoniae; PseudomoNot founds aeruginosa; Salmonella enterica; Shigella dysenteriae; Shigella flexneri; Shigella sonnei | Not found | Chromosome mediated | K18589 | ACCESSORY
|
| dfrA7 | Acinetobacter_baumannii_strain_BM4674 | ACS44716.1 | dihydrofolate reductase type A7 | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Enterobacter cloacae; Klebsiella pneumoniae; Salmonella enterica | mobile_element_type=integron:class I | Chromosome mediated | K18589 | ACCESSORY
|
| dhfrI | Acinetobacter_baumannii_AYE | WP_000777554.1 | Dihydrofolate reductase (EC 1.5.1.3) | NA | Trimethoprim | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | K18589 | ACCESSORY
|
| QnrVC6 | Acinetobacter_baumannii_strain_NF141757 | AGR45340.1 | aminoglycoside 6'-N-acetyltransferase | fluoroquinolone antibiotic | Not mapped | target modification | antibiotic target protection | quinolone resistance protein (qnr) | Not found | integron:class 1 integron | Chromosome mediated | K19278 | ACCESSORY
|
| ABO12487.2 | Acinetobacter_baumannii_ATCC_17978 | ABO12487.2 | putative dehydratase | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | not mapped | CORE
|
| WP_001097357.1 | Acinetobacter_baumannii_SDF | WP_001097357.1 | dehydratase | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | not mapped | CORE
|
| WP_001097347 | Acinetobacter baumannii | WP_001097347.1 | Probable (3R)-hydroxyacyl-CoA dehydratase HtdX | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | not mapped | CORE
|
| fabG | Acinetobacter_baumannii_ATCC_17978 | WP_011859543.1 | 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);FabG4 | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | K00059 | CORE
|
| GyrA | Acinetobacter_baumannii_strain_A1 | AJF82744.1 | GyrA | fluoroquinolone antibiotic;nybomycin | Not mapped | target modification | antibiotic target alteration | DNA gyrase | Not found | Not found | Chromosome mediated | K02469 | CORE
|
| ParC | Acinetobacter_baumannii_strain_D36 | ALJ89624.1 | ParC | fluoroquinolone antibiotic;nybomycin | Not mapped | target modification | antibiotic target alteration | DNA gyrase (fluoroquinolone resistant parC) | Not found | Not found | Chromosome mediated | K02621 | CORE
|
| FolA | Acinetobacter_baumannii_isolate_K50 | SPC58454.1 | dihydrofolate reductase type 7 | diaminopyrimidine antibiotic | Not mapped | target modification | antibiotic target alteration | Dihydrofolate reductase | Not found | Not found | Chromosome mediated | K18589 | ACCESSORY
|
| LpxA | Acinetobacter_baumannii | AJF82049.1 | LpxA | peptide antibiotic | Colistin | target modification | antibiotic target alteration | Lipopolysaccharide | Not found | Not found | Chromosome mediated | K00677 | CORE
|
| LpxC | Acinetobacter_baumannii_strain_A1 | AJF83452.1 | LpxC | peptide antibiotic | Colistin | target modification | antibiotic target alteration | Lipopolysaccharide | Not found | Not found | Chromosome mediated | K02535 | CORE
|
| LpxD | Acinetobacter_baumannii_strain_A1 | AJF82051.1 | LpxD | peptide antibiotic | Colistin | target modification | antibiotic target alteration | Lipopolysaccharide (Acinetobacter mutant Lpx gene conferring resistance to colistin) | Not found | Not found | Chromosome mediated | K02536 | CORE
|
| sul1 | Acinetobacter_baumannii_strain_AR_0083 | AVN26507.1 | hypothetical protein;sulfonamide-resistant dihydropteroate synthase Sul1;quaternary ammonium compound efflux SMR transporter QacE delta 1 | sulfone antibiotic;sulfonamide antibiotic | Not mapped | target modification | antibiotic target replacement | sulfonamide resistant sul | Enterobacter aerogenes; Enterobacter cloacae; Enterococcus faecium; Klebsiella pneumoniae; PseudomoNot founds aeruginosa; Salmonella enterica; Shigella dysenteriae; Shigella flexneri; Shigella sonnei | Not found | Chromosome mediated | K18974 | ACCESSORY
|
| QnrB10 | Acinetobacter_baumannii_strain_M3AC9-7 | AIL25536.1 | QnrB19 (quinolone resistance protein) | fluoroquinolone antibiotic | Levofloxacin; Sparfloxacin; Ciprofloxacin; DetermiNot mappednt of fluoroquinolone resistance; Not mappedlidixic acid; Moxifloxacin; Norfloxacin; Gatifloxacin | target modification | antibiotic target protection | quinolone resistance protein | Enterobacter cloacae; Klebsiella pneumoniae; Salmonella enterica; Shigella sonnei | mobile_element_type=transposon:Tn5387 | Chromosome mediated | K18555 | Not mapped
|
| dfrA12 | Acinetobacter_baumannii_strain_SMSZ2 | ANQ47254.1 | dihydrofolate reductase | diaminopyrimidine antibiotic | trimethoprim | target modification | antibiotic target replacement | trimethoprim resistant dihydrofolate reductase dfr | Enterobacter aerogenes; Enterobacter cloacae; Enterococcus faecium; Klebsiella pneumoniae; Salmonella enterica;Shigella sonnei | Not found | Chromosome mediated | K18590 | Not mapped
|
