| Gene name |
Strain |
Protein ID |
Product |
Drug class |
Antibiotic name |
Broad MOR |
MOR |
Enzyme class |
Similar mechanisms in other species |
IS elements |
Chromosome vs plasmid mediated |
Pathway |
Pan genome |
| dfrA10 | Acinetobacter_baumannii__str._AYE | CAM88389.1 | "Dihydrofolate reductase type A10 (Dihydrofolate
reductase type X) (DHFRX)" | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Klebsiella pneumoniae; Salmonella enterica | Not found | Chromosome mediated | K19643 | Not mapped
|
| dfrA1 | Acinetobacter_baumannii_Aci20 | WP_071846293.1 | trimethoprim-resistant dihydrofolate reductase DfrA1 | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Enterobacter aerogenes; Enterobacter cloacae; Klebsiella pneumoniae; PseudomoNot founds aeruginosa; Salmonella enterica; Shigella dysenteriae; Shigella flexneri; Shigella sonnei | Not found | Chromosome mediated | K18589 | ACCESSORY
|
| dfrA7 | Acinetobacter_baumannii_strain_BM4674 | ACS44716.1 | dihydrofolate reductase type A7 | diaminopyrimidine antibiotic | Trimethoprim | target modification | antibiotic target replacement | Trimethoprim resistant dihydrofolate reductase dfr | Enterobacter cloacae; Klebsiella pneumoniae; Salmonella enterica | mobile_element_type=integron:class I | Chromosome mediated | K18589 | ACCESSORY
|
| dhfrI | Acinetobacter_baumannii_AYE | WP_000777554.1 | Dihydrofolate reductase (EC 1.5.1.3) | NA | Trimethoprim | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | K18589 | ACCESSORY
|
| ABO12487.2 | Acinetobacter_baumannii_ATCC_17978 | ABO12487.2 | putative dehydratase | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | not mapped | CORE
|
| WP_001097357.1 | Acinetobacter_baumannii_SDF | WP_001097357.1 | dehydratase | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | not mapped | CORE
|
| WP_001097347 | Acinetobacter baumannii | WP_001097347.1 | Probable (3R)-hydroxyacyl-CoA dehydratase HtdX | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | not mapped | CORE
|
| fabG | Acinetobacter_baumannii_ATCC_17978 | WP_011859543.1 | 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35);FabG4 | NA | Not mapped | target modification | antibiotic target replacement | NA | Not found | Not found | Chromosome mediated | K00059 | CORE
|
| sul1 | Acinetobacter_baumannii_strain_AR_0083 | AVN26507.1 | hypothetical protein;sulfonamide-resistant dihydropteroate synthase Sul1;quaternary ammonium compound efflux SMR transporter QacE delta 1 | sulfone antibiotic;sulfonamide antibiotic | Not mapped | target modification | antibiotic target replacement | sulfonamide resistant sul | Enterobacter aerogenes; Enterobacter cloacae; Enterococcus faecium; Klebsiella pneumoniae; PseudomoNot founds aeruginosa; Salmonella enterica; Shigella dysenteriae; Shigella flexneri; Shigella sonnei | Not found | Chromosome mediated | K18974 | ACCESSORY
|
| dfrA12 | Acinetobacter_baumannii_strain_SMSZ2 | ANQ47254.1 | dihydrofolate reductase | diaminopyrimidine antibiotic | trimethoprim | target modification | antibiotic target replacement | trimethoprim resistant dihydrofolate reductase dfr | Enterobacter aerogenes; Enterobacter cloacae; Enterococcus faecium; Klebsiella pneumoniae; Salmonella enterica;Shigella sonnei | Not found | Chromosome mediated | K18590 | Not mapped
|
